How Active Vitamin B12 (HoloTC) appears on your report

Look for Active Vitamin B12 (HoloTC). The result is normally shown in pmol/L, next to the reference interval used by the laboratory that ran the test.

Note the collection date before you compare it with anything, along with the context that matters for this marker: diet, absorption, supplements and medicines can affect it. Read it with total B12, folate, homocysteine and the full blood count when relevant.

Active Vitamin B12 (HoloTC) range in Australia

Vector tracks Active Vitamin B12 (HoloTC) against an optimal range of 35–200 pmol/L. Australia has no nationally harmonised reference interval for this marker, so the interval printed on your report varies with the laboratory and the assay it used.

Vector optimal35
200pmol/L
Varies by laboratory

No harmonised Australian interval exists for this marker — use the one printed beside your own result.

Vector’s optimal range is the band the app tracks against and the one printed in the doctor report. Why the two differ.

What to read alongside Active Vitamin B12 (HoloTC)

A single marker rarely explains itself. These results are commonly interpreted together with Active Vitamin B12 (HoloTC), and Vector keeps them within reach of each other as your record grows.

Tracking Active Vitamin B12 (HoloTC) over time

One Active Vitamin B12 (HoloTC) result is a single point. Import the report into Vector, check the extracted value, unit and collection date, and it becomes the start of a series instead — with each later report adding a dated point you can actually compare against.

Further reading

Active Vitamin B12 (HoloTC) is read the same way every other result on the report is. These two guides cover that method rather than this marker:

Common questions

What is a normal Active Vitamin B12 (HoloTC) range in Australia?

Australia has no nationally harmonised reference interval for Active Vitamin B12 (HoloTC), so the range printed on your report varies with the laboratory and the assay it used — always read your result against the interval beside it. Vector tracks Active Vitamin B12 (HoloTC) against an optimal range of 35–200 pmol/L, which is deliberately tighter than a population reference interval.

What is the optimal Active Vitamin B12 (HoloTC) level?

Vector treats 35–200 pmol/L as the optimal range for Active Vitamin B12 (HoloTC). An optimal range is a target the app tracks against, not a clinical threshold, and it can differ from the interval your laboratory prints.

What unit is Active Vitamin B12 (HoloTC) reported in on Australian pathology reports?

Active Vitamin B12 (HoloTC) is usually reported in pmol/L on Australian pathology reports. The performing laboratory prints a reference interval in the same unit beside the result, and that interval is the one that governs your individual result.

What can change your Active Vitamin B12 (HoloTC) result?

Diet, absorption, supplements and medicines can affect it. Read it with total B12, folate, homocysteine and the full blood count when relevant.

Sources

  1. RCPA Manual: HolotranscobalaminAustralian pathology reference for this test and related result context.
  2. Healthdirect: vitaminsGeneral consumer context for nutrient testing and supplementation.

Published 2 August 2026 · Updated 3 August 2026 · Author Vector